A region is a unit of chapters. The regions are Northeast, Southeast, Middlewest, Middlesouth and Southwest. The Regional Director is the administrator of the region, provides guidance and direction to the chapters and presides over the affairs of the region and the annual Regional meeting. The Regional Director represents the chapters on the Board of Directors and reports to the Supreme Basileus, the Board of Directors and to the Boule'.

The Directors of these regions are:

Gwendylon Johnson, MA, RNC
Northeast Region

Georgia Faye Jackson, MPH, RN
Southeast Region

Serena Sanford, MSN, RN
Middlesouth Region

Marcellette Carter
Middlewest Region

Joy Powell
Southwest Region